1) Infected Edges: Hole and Cut type wounds, possibly others, will randomly become worse with no event log indication. This could affect how easily you're able to skill with a wound, and possibly cause death if you're afkor not paying attention. I "mined" data from my event logs for the past 2 months and found 3 different versions of this wound condition and about 8 separate infection events.
3) Duration of Infected Edges Condition: Infected Edges last between a few minutes and a few hours real life. The longest continuous Infected Edges event I've observed, lasted about 23 real life hours (8 hours logged in). Once you get an infection, the duration and whether it gets better or worse seems to be random and most of the infections I observed only got better.
The time between when you get the original wound and when an Infected Edges starts, also appears to be random; I've gotten them 10 mins after getting a wound and after several hours. Infected Edges have also been observed to appear and dissapear on the same wound 2 or 3 times over several real days.